Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Monday, July 7, 2014

Neuroaid - MLC 901, A Traditional Chinese Medicine Induces Neuroprotective and Neuroregenerative Benefits After Traumatic Brain Injury in Rats

I don't have a good enough scientific background to see if this research is valid and reverses the previous negative results for stroke.

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Neuroaid - It’s sold in 25 countries and 20,000 people have taken it, but herbal remedy proves no better than placebo in trial 

Chinese herbal remedy for stoke recovery no better than placebo

CAM taking advantage of stroke patients 

Neuroaid and stroke rehab 

And Peter Levines' comments on it here: 

Neuroaid: Partial Truth and Petty Theft

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  The TBI Neuroaid result here:

http://www.sciencedirect.com/science/article/pii/S0306452214005326
Under a Creative Commons license
  Open Access

Highlights

MLC901 prevented the serum increase of two biomarkers S100B and NSE.
MLC901 reduced the infarct volume up to 2 hours post-TBI.
MLC901 prevented the edema formation and assists resolution, via the aquaporin 4.
MLC901 induced an increase of neurogenesis and gliogenesis around the lesion.
MLC901 reduced cognitive deficits induced by TBI.

Abstract

Traumatic brain injury is a frequent and clinically highly heterogeneous neurological disorder with large socioeconomic consequences. NeuroAid (MLC601 and MLC901), a Traditional Medicine used in China for patients after stroke has been previously reported to induce neuroprotection and neuroplasticity. This study was designed to evaluate the neuroprotective and neuroregenerative effects of MLC901 in a rat model of traumatic brain injury (TBI). TBI was induced by a moderate lateral fluid percussion applied to the right parietal cortex. MLC901 was injected intraperitoneally at 2 hours post-TBI, and then administered in drinking water at a concentration of 10 mg/ml until sacrifice of the animals. The cognitive deficits induced by TBI were followed by using the “what-where-when” task, which allows the measurement of episodic-like memory. MLC901 treatment decreased brain lesions induced by TBI. It prevented the serum increase of S100B and NSE, which may be markers to predict the neurologic outcome in human patients with TBI. MLC901 reduced the infarct volume when injected up to 2 hours post-TBI, prevented the edema formation and assisted its resolution, probably via the regulation of aquaporin 4. These positive MLC901 effects were associated with an upregulation of VEGF as well as an increase of endogenous hippocampal neurogenesis and gliogenesis around the lesion. Furthermore, MLC901 reduced cognitive deficits induced by TBI. Rats subjected to TBI displayed a suppression of temporal order memory, which was restored by MLC901. This work provides evidence that MLC901 has neuroprotective and neurorestorative actions, which lead to an improvement in the recovery of cognitive functions in a model of traumatic brain injury.

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