Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Saturday, August 9, 2014

Delayed atrophy in posterior cingulate cortex and apathy after stroke

I expect that you don't want any atrophy of your brain. What is your doctor doing to prevent that?
http://onlinelibrary.wiley.com/doi/10.1002/gps.4185/abstract;jsessionid=34895A2A986FD27E5D98A6DF215F480C.f01t01?
  1. Kiwamu Matsuoka1,
  2. Fumihiko Yasuno1,2,*,
  3. Akihiko Taguchi3,4,
  4. Akihide Yamamoto2,
  5. Katsufumi Kajimoto3,
  6. Hiroaki Kazui5,
  7. Takashi Kudo5,
  8. Atsuo Sekiyama6,
  9. Soichiro Kitamura1,
  10. Kuniaki Kiuchi1,
  11. Jun Kosaka1,
  12. Toshifumi Kishimoto1,
  13. Hidehiro Iida2 and
  14. Kazuyuki Nagatsuka3
Article first published online: 5 AUG 2014
DOI: 10.1002/gps.4185
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Keywords:

  • stroke;
  • apathy;
  • magnetic resonance imaging;
  • voxel-based morphometric analysis;
  • posterior cingulate cortex

Objective

A few studies have been performed on chronic structural changes after stroke. The primary purpose of the present study was to investigate regional cortical volume changes after the onset of stroke and to examine how the cortical volume changes affected neuropsychiatric symptoms.

Methods

Participants were 20 stroke patients and 14 control subjects. T1-MRI was performed twice, once at the subacute stage and again 6 months later, and whole brain voxel-based morphometric (VBM) analysis was used to detect significant cortical gray matter volume changes in patients. We also assessed the correlation between changes in cortical volumes and changes in neuropsychiatric symptoms during the 6 months following a stroke.

Results

In the present study, we found significant volume reductions in the anterior part of the posterior cingulate cortex (PCC) over the 6 months following a stroke by exploratory VBM analysis. We also found that the amount of volume change was significantly correlated with the change in apathy-scale scores during the 6 months poststroke.

Conclusions

The present study suggests that delayed atrophic change is evident in the PCC 6 months after a stroke. There was greater apathetic change in the stroke patients with the larger volume reductions. The delayed atrophy of the PCC may reflect degeneration secondary to neuronal loss due to stroke. Such degeneration might have impaired control of goal-directed behavior, leading to the observed increase in apathy.
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