Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Wednesday, August 6, 2014

How coffee protects against Parkinson’s

I'm doing lots of coffee for the dementia prevention part.
http://www.alphagalileo.org/ViewItem.aspx?ItemId=143597&CultureCode=en
A specific genetic variation discovered by researchers at Linköping University in Sweden protects against Parkinson’s Disease – especially for those who drink a lot of coffee.
The study is published in the scientific journal PLOS One.
Hereditary and environmental factors interact with one another in the emergence of diseases, and research is often focussed on identifying genes and exposures that increase the risk for contracting diseases. But there are also genetic variations – mutations – and environmental factors that protect against the emergence of certain diseases.
Neurodegenerative diseases such as Parkinson’s have a complicated background where both genetic factors and exposure to environmental factors are involved.  In a study of a million genetic malformations, the research team identified a variant of the GRIN2A gene as a protective factor against Parkinson's. The corresponding protein is part of a complex that is thought to play a role in several neurodegenerative diseases.
An epidemiological study of Parkinson’s patients from two counties in south east Sweden examined a combination of a previously known protective factor – caffeine – and the genetic variant in GRIN2A. The findings show that individuals with this combination run a significantly lower risk of developing the disease.
The study gives a molecular explanation to the protective effects that increased caffeine intake has on the development of Parkinson’s.  Caffeine integrates with a dopamine receptor that regulates the flow of calcium into the cell. As dopamine is part of the human reward system, and the interaction of caffeine with it, it has been speculated that individuals with certain genetic variations are not “rewarded” to the same extent by a cup of coffee, and therefore would not enjoy the same protective effect as others. The newly published study shows that GRIN2A can be a part of such a genetic predisposition.
The study was conducted with financial support from the Foundation for Parkinson's Research at Linköping University.

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