Changing stroke rehab and research worldwide now.Time is Brain! trillions and trillions of neurons that DIE each day because there are NO effective hyperacute therapies besides tPA(only 12% effective). I have 523 posts on hyperacute therapy, enough for researchers to spend decades proving them out. These are my personal ideas and blog on stroke rehabilitation and stroke research. Do not attempt any of these without checking with your medical provider. Unless you join me in agitating, when you need these therapies they won't be there.

What this blog is for:

My blog is not to help survivors recover, it is to have the 10 million yearly stroke survivors light fires underneath their doctors, stroke hospitals and stroke researchers to get stroke solved. 100% recovery. The stroke medical world is completely failing at that goal, they don't even have it as a goal. Shortly after getting out of the hospital and getting NO information on the process or protocols of stroke rehabilitation and recovery I started searching on the internet and found that no other survivor received useful information. This is an attempt to cover all stroke rehabilitation information that should be readily available to survivors so they can talk with informed knowledge to their medical staff. It lays out what needs to be done to get stroke survivors closer to 100% recovery. It's quite disgusting that this information is not available from every stroke association and doctors group.

Wednesday, April 27, 2016

Nanograft Seeded with Three Cell Types Promotes Blood Vessel Formation to Speed Wound Healing

Do we need this to support neurogenesis and new stem cells? Build this into the scaffolding needed for stem cells?  Ask your doctor.
http://www.alphagalileo.org/ViewItem.aspx?ItemId=163529&CultureCode=en

Large or slow-healing wounds that do not receive adequate blood flow could benefit from a novel approach that combines a nanoscale graft onto which three different cell types are layered. Proper cell alignment on the nanograft allows for the formation of new blood vessel-like structures, as reported in of Tissue Engineering, Part A, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers (http://www.liebertpub.com/). The article is available free for download on the Tissue Engineering (http://online.liebertpub.com/doi/full/10.1089/ten.tea.2015.0461) website until May 26, 2016.
Tae Hee Kim, Soo Hyun Kim, PhD, Kam Leong, PhD, and Youngmee Jung, PhD, Korea Institute of Science and Technology, Korea University, Korea University of Science and Technology (Seoul, Korea) and Columbia University (New York, NY), describe the nanoscale topography and triculture technology they used to create a microenvironment that mimics what occurs in normal tissue and can promote angiogenesis. They demonstrate how the shape, width, and depth of the nanograft all affected the behavior of the cells and the formation of stable capillary-like tubular structures.
In the article "Nanografted Substrata and Triculture of Human Pericytes, Fibroblasts, and Endothelial Cells for Studying the Effects on Angiogenesis (http://online.liebertpub.com/doi/full/10.1089/ten.tea.2015.0461)," the researchers describe how this technique could be applicable for treating wounds that do not heal well naturally.
"The combination of advanced materials and polycellular administration is opening new paths to the all-important requirement for angiogenesis in tissue engineering," says Co-Editor-in-Chief Peter C. Johnson, MD, Principal, MedSurgPI, LLC and President and CEO, Scintellix, LLC, Raleigh, NC.

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